Normal and Pathological Physiology

A person responsible for the delivery, development, and quality of the study programme:

prof. Fedor Šimko, MD, PhD.

Intitute of Pathological Physiology FM CU, Sasinkova 4, Bratislava



Teachers of the profile subject:

prof. Beata Mladosievičová, MD, PhD.

Assoc. prof. Tomáš Baka, MD, PhD.

Assoc. prof. Jana Radošinská, MD, PhD.


Study advisor of the study programme:

prof. Fedor Šimko, MD, PhD., e-mail: (personal contact after agreement via e-mail)


List of the supervisors:

prof. MUDr. Fedor Šimko, CSc., prof. MUDr. Beata Mladosievičová, CSc., doc. MUDr. Jana Radošinská, PhD., doc. MUDr. Tomáš Baka, PhD., MUDr. Mgr. Ľudovít Paulis, PhD., doc. MUDr. Ing. RNDr. Peter Celec, DrSc., MPH, prof. MUDr. Boris Mravec, PhD., prof. MUDr. Daniela Ostatníková, PhD., prof. MUDr. Marián Bernadič, CSc., doc. RNDr. Jana Muchová, PhD., doc. PharmDr. Vladimír Jakuš, CSc., doc. MUDr. Katarína Šebeková, DrSc., doc. Ing. Ingrid Žitňanová, PhD., prof. MUDr. Peter Turčáni, PhD., doc. MUDr. Mária Bucová, CSc., mim. prof., prof. MUDr. Ladislav Turecký, CSc., prof. Ing. Zdeňka Ďuračková, PhD., doc. RNDr. Ľuboš Danišovič, PhD., prof. RNDr. Vanda Repiská, PhD., doc. MUDr. RNDr. Roman Gardlík, PhD., doc. RND. Ľubomíra Tóthová, PhD., doc. MUDr. Mgr. Július Hodosy, PhD., doc. RNDr. Monika Barteková, PhD., doc. RNDr. Ján Bakoš, PhD., doc. RNDr. Vladimíra Ďurmanová, PhD., doc. Mgr. Ivana Shawkatová, PhD., prof. MUDr. Peter Boor, PhD., Mgr. Michal Pastorek, PhD., doc. Dr. Aleksandra Sashova Tomova, PhD., Mgr. Katarína Janšáková, PhD., Mgr. Veronika Borbélyová, PhD., Mgr. Emese Renczés, PhD., Mgr. Barbora Konečná, PhD., prof. PharmDr. Ján Kyselovič, PhD., doc. MUDr. Katarína Babinská, PhD.,  prof. MUDr. Barbara Ukropcová, PhD.

RNDr. Iveta Bernátová, DrSc., doc. RNDr. Oľga Pecháňová, DrSc., RNDr. Soňa Čačanyiová, PhD., doc. RNDr. Monika Barteková, PhD., MUDr. Táňa Ravingerová, DrSc., FIACS, MUDr. Igor Riečanský, PhD., RNDr. Martina Cebová, PhD., RNDr. Narcisa Tribulová, DrSc., MUDr. Ima Dovinová, PhD., RNDr. Ivo Juránek, PhD., prof. PharmDr. Daniela Ježová, DrSc., doc. MUDr. Juraj Staník, PhD., MUDr. RNDr. Lukáš Varga, PhD., Mgr. Jozef Ukropec, DrSc., Ing. Alexandra Záhradníková, PhD., RNDr. Michal Cagalinec, PhD., RNDr. Alexandra Záhradníková, PhD. 


Place/s of realisation of the study programme:

The Medical Faculty, Comenius University in Bratislava and its parts seat, including clinical workplaces, which are part of university hospitals providing an education of students at Faculty of Medicine, CU in Bratislava, with which the university has concluded ‘Contracts on practical training’ (University Hospital Bratislava, National Institute for Children's Diseases, Merciful Brothers University Hospital, St. Elizabeth Cancer Institute, National Oncological Institute, National Institute of Cardiovascular Disease)


Awarded academic degree: doctor ("philosophiae doctor", in short, "PhD. ")


The language in which the programme is organised: Slovak, English


The standard length of study in academic years: four years (internal form) / five years (external form)


Graduate profile and learning objectives:  

The content of the PhD study program is focused on the study of physiological and pathological processes of altered functions of individual organs and systems of the human body. During the doctoral study, the students acquires knowledge in the field of physiology, pathological physiology, biochemistry of behavioral manifestations and examination methods from several preclinical and clinical areas, which contribute to clarifying the functional status of individual tissue and organ systems. In the course of the study the students will learn to independently formulate a scientific problem, formulate a scientific hypothesis, prepare and implement a scientific experiment, use laboratory and clinical non-invasive, semi-invasive and invasive research methods, objectively evaluate the obtained results and perform adequate statistical analysis. The main goal of these activities will be theoretical as well as practical mastery of methods that are standardly used in experimental and clinical research of functional disorders. Graduates of the study program will focus not only on the detection of functional disorders in specific physiological and pathological conditions, but the aim of their education is to gain the ability to critically analyze and synthesize the results of measurements with the possibility of their therapeutic influence based on detailed knowledge of their pathophysiological nature. The requirement to complete the study program is also the ability to present their own research results to the professional public at conferences and scientific events and in the form of publishing articles in professional journals. The results of creative experimental work not only contribute to the development of science and scientific knowledge, but their proper scientific value allows their clinical application in various fields of medicine, especially in internal medicine and pediatrics, neurology and surgical disciplines



Graduates of the presented doctoral study program are currently in demand mainly at the workplaces of the Ministry of Health, such as the department of internal medicine and pediatrics, neurology, cardiology, psychiatry and psychology, and clinical pharmacology. Graduates of doctoral studies can work within the Ministry of Education as university teachers or researchers at universities with a focus on medicine, health sciences, public health, such as physiology, pathophysiology, pathological anatomy, biochemistry, pharmacology, genetics and biology. Graduates of the presented study program at the Medical Faculty of Comenius University in Bratislava master a wide range of scientific methods used in biomedical research such as physiology and pathophysiology, biochemistry, pharmacology, behavioral medicine, neurology, which are able to apply creatively in their work and contribute to the development of scientific knowledge. They have the prerequisites for successful application in leading teams in a wide range of scientific and research institutions focused on medical, veterinary or pharmaceutical sciences, they are professionally prepared to work creatively in scientific institutes of the Slovak Academy of Sciences at various levels of research. Other professions, which, however, require the completion of an accredited study program of specialized studies in the medical profession, include physician - internist, pediatrician, neurologist, anesthetist, clinical pharmacologist, psychiatrist, cardiologist, clinical geneticist.


Evaluation of the study programme quality by employers:

A request to assess the quality of the submitted study programme was sent to selected employers to express their opinion on the need for a new doctoral study programme focused on medical biology and clinical genetics. Delivered letters are available at the Department of scientific-research activities, doctoral studies and international relationships of the Faculty of Medicine, Comenius University in Bratislava